Olympique Lyonnais will approach their Europa League opening fixture against RSC Anderlecht with a markedly altered lineup, signalling head coach Paulo Fonseca’s intent to balance European ambition with domestic demands. The Belgian clash, scheduled for Wednesday evening, arrives just days after Lyon’s Ligue 1 calendar pits them against Stade Rennais, a club widely tipped as a contender for this season’s Champions League spots. By rotating heavily, Fonseca aims to preserve freshness for the grueling stretch ahead while still fielding a side capable of advancing beyond the group stage.

The projected eleven reflects a blend of experience and youthful promise. Goalkeeper Rémy Descamps is set to start between the posts, taking over from Dominik Greif who has featured regularly in recent league outings. The